The Massachusetts-based biotechnology firm finished second last year.
Biogen edged out fellow American pharmaceutical company Allergan, which placed second in its Global 100 debut. German sportswear company Adidas finished third, followed by Singaporean real estate corporation Keppel Land and Finnish retailing conglomerate Kesko, in fifth place.
The US dominates the list, with 20 companies making the ranks. This is the US’ best showing in the 11-year history of the Global 100.